更新日：2023年1月5日

奥山上席専門研究員の執筆した論文がJapanese Journal of Radiologyにonline掲載されました。

• 日付
  2023.01
• 掲載日
  2022年12月28日
• 雑誌名
  Japanese Journal of Radiology （Published 28 December 2022）
• 題名
  FDG–PET fndings associated with various medical procedures and treatments
• 要旨
  [18F]-fluorodeoxyglucose (FDG) positron emission tomography (PET) is a well-established modality with high sensitivity for the diagnosis and staging of oncologic patients. FDG is taken up by the glucose transporter of the cell membrane and becomes trapped within the cell.
  In addition to malignant neoplasms, active inflammatory lesions and some kinds of benign tumors also accumulate FDG.
  Moreover, the degree of uptake into normal organs and tissues depends on various physiological conditions, which is affected by various medical procedures, treatments, and drugs. To avoid misleading interpretations, it is important to recognize possible situations
  of unexpected abnormal accumulation that mimic tumor lesions. In this review, we present various FDG findings associated with surgical or medical procedures and treatments. Some findings reflect the expected physiological reaction to treatment, and some show inflammation due to prior procedures.
  Occasionally, FDG–PET visualizes other disorders that are unrelated to the malignancy, which may be associated with the adverse effects of certain drugs that the patient is taking. Careful review of medical records and detailed interviews of patients are thus necessary.
• 日本語要旨
  FDG-PETは腫瘍の病期分類や再発診断に重要なモダリティである。しかし、グルコーストランスポータによって取り込まれるFDGの集積機序は、腫瘍に特異性の高いものではなく、様々の炎症や、生理的状況によっても高集積を示すものがある。
  本論文では、様々の医療手技や、治療、薬剤によって生じうる反応性集積や、副作用によるFDG所見をレビューした。診断の際には、カルテ記録の念入りなチェックや、患者本人への聴取が重要となる。